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ERK2 Recombinant Rabbit mAb
db11918
Datasheet
- Background This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jan 2014]
- Immunogen A synthetic peptide of human ERK2
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Gene ID
5594
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Swiss Prot
P28482
- Synonyms ERK; p38; p40; p41; ERK2; ERT1; ERK-2; MAPK2; PRKM1; PRKM2; P42MAPK; p41mapk; p42-MAPK
- Reactivity Human, Mouse, Rat
- Application WB, IHC, ICC/IF, FC
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Recommended dilution
WB: 1:1000
IHC: 1:100
ICC/IF: 1:200-1:2000
FC: 1:200-1:1000 - Calculated MW 41 kDa
- Observed MW 41 kDa
- Host species Rabbit
- Clonality Monoclonal
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of p42 MAPK (ERK2) in K562,Rat Brain,C6,3T3,Hela cell lysates using p42 MAPK (ERK2) antibody(1:1000 diluted). -
Western blot analysis of extracts from Jurkat,HCT116 cells using db11918 at 1:1000. -
Immunohistochemical analysis of paraffin-embedded human Cholangiocarcinoma using db11918 antibody. -
Immunofluorescent analysis of K562 cells using db11918 antibody (green), and DAPI (blue).
订购信息
- Package Price (RMB)
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
