Phospho-MEK1 (Ser298) Recombinant Rabbit mAb - diagbio | 戴格生物

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Phospho-MEK1 (Ser298) Recombinant Rabbit mAb

db11915

Datasheet

Product Name : Phospho-MEK1 (Ser298) Recombinant Rabbit mAb

Cat.No.: db11915

Synonyms : CFC3; MEK1; MKK1; MAPKK1; PRKMK1

Application : WB, IHC-P, ICC/IF, FC

Reactivity : Human,Mouse,Rat

Host species : Rabbit

Background The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. [provided by RefSeq, Jul 2008]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser298 of human MEK1
Gene ID 5604
Swiss Prot Q02750
Synonyms CFC3; MEK1; MKK1; MAPKK1; PRKMK1
Reactivity Human,Mouse,Rat
Application WB, IHC-P, ICC/IF, FC
Recommended dilution WB: 1:1000-1:5000
IHC-P: 1:50
ICC/IF: 1:100-1:200
FC: 1:100
Calculated MW 43 kDa
Observed MW 43 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of Phospho-MEK1 (Ser298) in C6,3T3,Hela cell lysates using Phospho-MEK1 (Ser298) antibody(1:1000 diluted).
Western blot analysis of extracts from HCT116 cells and Mouse brain tissue using db11915 at 1:1000.
Immunofluorescent analysis of HT-1080 cells using db11915 antibody (green), and DAPI (blue).

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