Phospho-TAK1 (Ser439) Recombinant Rabbit mAb - diagbio | 戴格生物

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Phospho-TAK1 (Ser439) Recombinant Rabbit mAb

db11892

Product Name : Phospho-TAK1 (Ser439) Recombinant Rabbit mAb

Cat.No.: db11892

Synonyms : CSCF; FMD2; TAK1; MEKK7; TGF1a

Application : WB, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser439 of human TAK1
Gene ID 6885
Swiss Prot O43318
Synonyms CSCF; FMD2; TAK1; MEKK7; TGF1a
Reactivity Human, Mouse, Rat
Application WB, IP
Recommended dilution WB: 1:1000
IP: 1:20
Calculated MW 67 kDa
Observed MW 78 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of TAK1 (Phospho-Ser439) in 3T3,C6,MCF7 cell lysates using TAK1 (Phospho-Ser439) antibody(1:1000 diluted).

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