DNA Nucleotidylexotransferase Recombinant Rabbit mAb - diagbio

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DNA Nucleotidylexotransferase Recombinant Rabbit mAb

db11889

Product Name : DNA Nucleotidylexotransferase Recombinant Rabbit mAb

Cat.No.: db11889

Synonyms : TDT

Application : WB, IHC

Reactivity : Human

Host species : Rabbit

Background This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008]
Immunogen Recombinant protein of human TdT
Gene ID 1791
Swiss Prot P04053
Synonyms TDT
Reactivity Human
Application WB, IHC
Recommended dilution WB: 1:2000
IHC: 1:50
Calculated MW 59 kDa
Observed MW 59 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of TdT in Jurkat cell lysates using TdT antibody(1:1000 diluted).

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