ATP Citrate lyase Recombinant Rabbit mAb - diagbio | 戴格生物

产品中心 Products Center

您当前的位置：

ATP Citrate lyase Recombinant Rabbit mAb

db11738

Product Name : ATP Citrate lyase Recombinant Rabbit mAb

Cat.No.: db11738

Synonyms : ACL; ATPCL; CLATP

Application : WB, IHC, ICC/IF, FC, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2014]
Immunogen A synthetic peptide of human ATP citrate lyase
Gene ID 47
Swiss Prot P53396
Synonyms ACL; ATPCL; CLATP
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC/IF, FC, IP
Recommended dilution WB: 1:2000-1:10000
IHC: 1:50
ICC/IF: 1:50
FC: 1:20
IP: 1:20
Calculated MW 121 kDa
Observed MW 121 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of ATP citrate lyase in K562,C6,3T3,Hela cell lysates using ATP citrate lyase antibody(1:1000 diluted).

订购信息