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eIF4E (DGR18881) Rabbit mAb
db11590
Datasheet
- Background The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
- Immunogen A synthetic peptide of human eIF4E
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Gene ID
1977
-
Swiss Prot
P06730
- Synonyms CBP; EIF4F; AUTS19; EIF4E1; eIF-4E; EIF4EL1
- Reactivity Human, Mouse, Rat
- Application WB, IHC, ICC/IF, FC, IP
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Recommended dilution
WB: 1:1000
IHC: 1:200-1:500
ICC/IF: 1:50
FC: 1:50
IP: 1:20 - Calculated MW 25 kDa
- Observed MW 25 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR18881
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of eIF4E in K562,Rat Brain,C6,3T3,Hela cell lysates using eIF4E antibody(1:1000 diluted). -
Western blot analysis of extracts from HepG2，HCT116 cells using db11590 at 1:5000. -
Immunohistochemical analysis of paraffin-embedded mouse colon using db11590 antibody.
订购信息
- Package Price (RMB)
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
