eIF4E Recombinant Rabbit mAb - diagbio | 戴格生物

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eIF4E Recombinant Rabbit mAb

db11590

Product Name : eIF4E Recombinant Rabbit mAb

Cat.No.: db11590

Synonyms : CBP; EIF4F; AUTS19; EIF4E1; eIF-4E; EIF4EL1

Application : WB, IHC, FC, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Immunogen A synthetic peptide of human eIF4E
Gene ID 1977
Swiss Prot P06730
Synonyms CBP; EIF4F; AUTS19; EIF4E1; eIF-4E; EIF4EL1
Reactivity Human, Mouse, Rat
Application WB, IHC, FC, IP
Recommended dilution WB: 1:5000
IHC: 1:20
FC: 1:20
IP: 1:20
Calculated MW 25 kDa
Observed MW 25 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of eIF4E in K562,Rat Brain,C6,3T3,Hela cell lysates using eIF4E antibody(1:1000 diluted).

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