MCM3 Recombinant Rabbit mAb
Product Name :
MCM3 Recombinant Rabbit mAb
Cat.No.:
db11512
Synonyms :
HCC5; P1.h; RLFB; P1-MCM3
Application :
IHC-P
Reactivity :
Human
Host species :
Rabbit
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Background
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012]
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Immunogen
A synthetic peptide of human MCM3
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Gene ID
4172
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Swiss Prot
P25205
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Synonyms
HCC5; P1.h; RLFB; P1-MCM3
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Reactivity
Human
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Application
IHC-P
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Recommended dilution
IHC-P: 1:100-1:200
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Calculated MW
91 kDa
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Observed MW
100 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of MCM3 in Jurkat,C6,Hela cell lysates using MCM3 antibody(1:1000 diluted).
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Immunohistochemical analysis of paraffin-embedded human tonsil using db11512 antibody.
订购信息
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Package
Price (RMB)
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20μL
698
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50μL
1398
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100μL
2398
- 货期:现货
For research use only. Not intended for diagnostic.