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MCM3 (DGR11254) Rabbit mAb
db11512
Datasheet
- Background The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012]
- Immunogen A synthetic peptide of human MCM3
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Gene ID
4172
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Swiss Prot
P25205
- Synonyms HCC5; P1.h; RLFB; P1-MCM3
- Reactivity Human
- Application IHC-P
- Recommended dilution IHC-P: 1:100-1:200
- Calculated MW 91 kDa
- Observed MW 100 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR11254
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of MCM3 in Jurkat,C6,Hela cell lysates using MCM3 antibody(1:1000 diluted). -
Immunohistochemical analysis of paraffin-embedded human tonsil using db11512 antibody.
订购信息
- Package Price (RMB)
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
