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MCM3 Recombinant Rabbit mAb
Alternate Text
db11512
Datasheet

Product Name : MCM3 Recombinant Rabbit mAb

Cat.No.: db11512

Synonyms : HCC5; P1.h; RLFB; P1-MCM3

Application : IHC-P

Reactivity : Human

Host species : Rabbit

  • Background The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012]
  • Immunogen A synthetic peptide of human MCM3
  • Gene ID 4172
  • Swiss Prot P25205
  • Synonyms HCC5; P1.h; RLFB; P1-MCM3
  • Reactivity Human
  • Application IHC-P
  • Recommended dilution IHC-P: 1:100-1:200
  • Calculated MW 91 kDa
  • Observed MW 100 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
  • Western blot detection of MCM3 in Jurkat,C6,Hela cell lysates using MCM3 antibody(1:1000 diluted).
  • Immunohistochemical analysis of paraffin-embedded human tonsil using db11512 antibody.
订购信息
  • Package Price (RMB)
  • 20μL 698
  • 50μL 1398
  • 100μL 2398
  • 货期:现货
For research use only. Not intended for diagnostic.