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FADD Recombinant Rabbit mAb
db11505
Datasheet
- Background Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis (By similarity). Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling (By similarity).
- Immunogen A synthetic peptide of mouse FADD
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Gene ID
14082
-
Swiss Prot
Q61160
- Synonyms Mort1/FADD
- Reactivity Mouse
- Application WB, IHC-P, ICC/IF, FC, IP
-
Recommended dilution
WB: 1:1000-1:5000
IHC-P: 1:50-1:100
ICC/IF: 1:50
FC: 1:20-1:50
IP: 1:20-1:50 - Calculated MW 23 kDa
- Observed MW 28 kDa
- Host species Rabbit
- Clonality Monoclonal
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of FADD in SHSY-5Y cell lysates using FADD antibody(1:1000 diluted). -
Immunohistochemical analysis of paraffin-embedded mouse liver using db11505 antibody.
订购信息
- Package Price (RMB)
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
