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FADD (DGR11188) Rabbit mAb
Alternate Text
db11505
Datasheet

Product Name : FADD (DGR11188) Rabbit mAb

Cat.No.: db11505

Synonyms : Mort1/FADD

Application : WB, IHC-P, ICC/IF, FC, IP

Reactivity : Mouse

Host species : Rabbit

  • Background Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis (By similarity). Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling (By similarity).
  • Immunogen A synthetic peptide of mouse FADD
  • Gene ID 14082
  • Swiss Prot Q61160
  • Synonyms Mort1/FADD
  • Reactivity Mouse
  • Application WB, IHC-P, ICC/IF, FC, IP
  • Recommended dilution WB: 1:1000-1:5000
    IHC-P: 1:50-1:100
    ICC/IF: 1:50
    FC: 1:20-1:50
    IP: 1:20-1:50
  • Calculated MW 23 kDa
  • Observed MW 28 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Clonality No. DGR11188
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
  • Western blot detection of FADD in SHSY-5Y cell lysates using FADD antibody(1:1000 diluted).
  • Immunohistochemical analysis of paraffin-embedded mouse liver using db11505 antibody.
订购信息
  • Package Price (RMB)
  • 20μL 698
  • 50μL 1398
  • 100μL 2398
  • 货期：现货
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For research use only. Not intended for diagnostic.