Daxx Recombinant Rabbit mAb - diagbio | 戴格生物

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Daxx Recombinant Rabbit mAb

db11451

Product Name : Daxx Recombinant Rabbit mAb

Cat.No.: db11451

Synonyms : DAP6; EAP1; BING2; SMIM40

Application : WB, IHC, ICC/IF, FC

Reactivity : Human

Host species : Rabbit

Background This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008]
Immunogen A synthetic peptide of human Daxx
Gene ID 1616
Swiss Prot Q9UER7
Synonyms DAP6; EAP1; BING2; SMIM40
Reactivity Human
Application WB, IHC, ICC/IF, FC
Recommended dilution WB: 1:2000
IHC: 1:20
ICC/IF: 1:20
FC: 1:20
Calculated MW 81 kDa
Observed MW 110 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of Daxx in HepG2,U251,HL-60 using Daxx antibody(1:1000 diluted).

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