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Phospho-PKC alpha (Ser657) Recombinant Rabbit mAb
db11446
Datasheet
- Background Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes. [provided by RefSeq, Jul 2008]
- Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser657 of human PKC alpha
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Gene ID
5578
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Swiss Prot
P17252
- Synonyms AAG6; PKCA; PRKACA; PKCI+/-; PKCalpha; PKC-alpha
- Reactivity Human, Mouse, Rat
- Application WB, IHC
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Recommended dilution
WB: 1:1000
IHC: 1:200 - Calculated MW 77 kDa
- Observed MW 80 kDa
- Host species Rabbit
- Clonality Monoclonal
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of PKC alpha (phospho-Ser657) in mouse Brain,Ramos using PKC alpha (phospho-Ser657) antibody(1:1000 diluted)
订购信息
- Package Price (RMB)
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
