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Hsp70 (DGR13507) Rabbit mAb
db11436
Datasheet
- Background Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones. The co-chaperones have been shown to not only regulate different steps of the ATPase cycle, but they also have an individual specificity such that one co-chaperone may promote folding of a substrate while another may promote degradation. The affinity for polypeptides is regulated by its nucleotide bound state.
- Immunogen Recombinant protein of mouse Hsp70
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Gene ID
15511
-
Swiss Prot
P17879
- Synonyms Hsp70; hsp68; Hsp70-1; Hsp70.1
- Reactivity Human,Mouse,Rat
- Application WB, IHC-P, ICC/IF, FC
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Recommended dilution
WB: 1:1000
IHC-P: 1:200-1:1000
ICC/IF: 1:50
FC: 1:100-1:200 - Calculated MW 70 kDa
- Observed MW 70 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR13507
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of Hsp70 in K562,Rat Brain,3T3,Hela cell lysates using Hsp70 antibody(1:1000 diluted). -
Immunohistochemical analysis of paraffin-embedded human tonsil using db11436 antibody.
订购信息
- Package Price (RMB)
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
