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ACTL6A Recombinant Rabbit mAb
db11424
Datasheet
- Background This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described. [provided by RefSeq, Jul 2008]
- Immunogen A synthetic peptide of human ACTL6A
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Gene ID
86
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Swiss Prot
O96019
- Synonyms Arp4; ACTL6; BAF53A; INO80K; ARPN-BETA
- Reactivity Human, Mouse, Rat
- Application WB, IHC, ICC/IF, IP
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Recommended dilution
WB: 1:1000
IHC: 1:20
ICC/IF: 1:50
IP: 1:20 - Calculated MW 48 kDa
- Observed MW 48 kDa
- Host species Rabbit
- Clonality Monoclonal
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of ACTL6A in Hela,MCF-7,HepG2,U2OS using ACTL6A antibody(1:1000 diluted).
订购信息
- Package Price (RMB)
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
