Caspase-9 Recombinant Rabbit mAb - diagbio | 戴格生物

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Caspase-9 Recombinant Rabbit mAb

db11292

Product Name : Caspase-9 Recombinant Rabbit mAb

Cat.No.: db11292

Synonyms : MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6

Application : WB, IP

Reactivity : Human, Mouse

Host species : Rabbit

Background This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
Immunogen Recombinant protein of human Caspase-9
Gene ID 842
12371
Swiss Prot P55211
Q8C3Q9
Synonyms MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6
Reactivity Human, Mouse
Application WB, IP
Recommended dilution WB: 1:1000
IP: 1:20
Calculated MW 46 kDa
Observed MW 46 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot analysis of extracts from Mouse heart tissue using db11292 at 1:1000.
Western blot analysis of extracts from MCF-7, Jurkat cells using db11292 at 1:1000.

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