Caspase-2 Recombinant Rabbit mAb - diagbio | 戴格生物

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Caspase-2 Recombinant Rabbit mAb

db11291

Product Name : Caspase-2 Recombinant Rabbit mAb

Cat.No.: db11291

Synonyms : ICH1; NEDD2; CASP-2; NEDD-2; PPP1R57

Application : WB, IHC, ICC/IF, FC

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Immunogen Recombinant protein of human Caspase-2
Gene ID 835
12366
64314
Swiss Prot P42575
P29594
P55215
Synonyms ICH1; NEDD2; CASP-2; NEDD-2; PPP1R57
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC/IF, FC
Recommended dilution WB: 1:1000
IHC: 1:200
ICC/IF: 1:200-1:500
FC: 1:200-1:500
Calculated MW 51 kDa
Observed MW 48 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot analysis of extracts from Jurkat cells using db11291 at 1:1000.
Western blot analysis of extracts from Jurkat,3T3,C6 cells using db11291 at 1:1000.

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