Phospho-MSK1 (Ser360) (DGR11224) Rabbit mAb - diagbio | 戴格生物

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Recombinant DGRmAb^®

Phospho-MSK1 (Ser360) (DGR11224) Rabbit mAb

db11273

Datasheet

Product Name : Phospho-MSK1 (Ser360) (DGR11224) Rabbit mAb

Cat.No.: db11273

Synonyms : MSK1; RLPK; MSPK1

Application : WB, ICC/IF

Reactivity : Human,Mouse,Rat

Host species : Rabbit

Background Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin. Plays an essential role in the control of RELA transcriptional activity in response to TNF and upon glucocorticoid, associates in the cytoplasm with the glucocorticoid receptor NR3C1 and contributes to RELA inhibition and repression of inflammatory gene expression.
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser360 of human MSK1
Gene ID 9252
Swiss Prot O75582
Synonyms MSK1; RLPK; MSPK1
Reactivity Human,Mouse,Rat
Application WB, ICC/IF
Recommended dilution WB: 1:2000-1:20000
ICC/IF: 1:100-1:200
Calculated MW 90 kDa
Observed MW 90 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR11224
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of Phospho-MSK1 (Ser360) in C6,CHO-K1 cell lysates using Phospho-MSK1 (Ser360) antibody(1:1000 diluted).
Immunofluorescent analysis of HeLa cells using db11273 antibody (green), and DAPI (blue).

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