BackgroundThis gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor. [provided by RefSeq, Apr 2009]
ImmunogenA synthetic peptide of human KDM4A/JHDM3A/JMJD2A
Storage/StabilityStore at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Western blot detection of KDM4A in Hela,A549,HL-60,U2OS,U87-MG cell lysates using KDM4A antibody(1:1000 diluted).
Western blot analysis of extracts from HCT116 cells using db11249 at 1:2000.