Acetyl-p53 (Lys370) (DGR19372) Rabbit mAb - diagbio | 戴格生物

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Recombinant DGRmAb^®

Acetyl-p53 (Lys370) (DGR19372) Rabbit mAb

db11223

Datasheet

Product Name : Acetyl-p53 (Lys370) (DGR19372) Rabbit mAb

Cat.No.: db11223

Synonyms : P53; BCC7; LFS1; TRP53

Application : WB, ICC/IF, FC, IP

Reactivity : Human,Mouse,Rat

Host species : Rabbit

Background This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
Immunogen A synthetic acetyl-peptide corresponding to residues surrounding Lys370 of human p53
Gene ID 7157
Swiss Prot P04637
Synonyms P53; BCC7; LFS1; TRP53
Reactivity Human,Mouse,Rat
Application WB, ICC/IF, FC, IP
Recommended dilution WB: 1:1000
ICC/IF: 1:200-1:500
FC: 1:100-1:200
IP: 1:100
Calculated MW 44 kDa
Observed MW 53 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR19372
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of Acetyl-p53 (Lys370) in Rat Brain lysates using Acetyl-p53 (Lys370) antibody(1:1000 diluted).
Immunofluorescent analysis of 3T3 cells using db11223 antibody (green), and DAPI (blue).

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