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Epac1 Recombinant Rabbit mAb
db11196
Datasheet
- Background Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP. Through simultaneous binding of PDE3B to RAPGEF3 and PIK3R6 is assembled in a signaling complex in which it activates the PI3K gamma complex and which is involved in angiogenesis. Plays a role in the modulation of the cAMP-induced dynamic control of endothelial barrier function through a pathway that is independent on Rho-mediated signaling. Required for the actin rearrangement at cell-cell junctions, such as stress fibers and junctional actin.
- Immunogen A synthetic peptide of human Epac1
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Gene ID
10411
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Swiss Prot
O95398
- Synonyms EPAC; EPAC1; bcm910; HSU79275; CAMP-GEFI
- Reactivity Human, Mouse, Rat
- Application WB, IHC
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Recommended dilution
WB: 1:1000-1:5000
IHC: 1:100 - Calculated MW 104 kDa
- Observed MW 104 kDa
- Host species Rabbit
- Clonality Monoclonal
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of Epac1 in 3T3 cell lysates using Epac1 antibody(1:1000 diluted).
订购信息
- Package Price (RMB)
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
