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ATM Recombinant Rabbit mAb
db11193
Datasheet
- Background The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. [provided by RefSeq, Aug 2010]
- Immunogen Recombinant protein of human ATM
-
Gene ID
472
-
Swiss Prot
Q13315
- Synonyms AT1; ATA; ATC; ATD; ATE; ATDC; TEL1; TELO1
- Reactivity Human, Mouse, Rat
- Application WB, ICC/IF, FC, IP, ChIP
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Recommended dilution
WB: 1:1000
ICC/IF: 1:50
FC: 1:100
IP: 1:20
ChIP: 1:20 - Calculated MW 351 kDa
- Observed MW 351 kDa
- Host species Rabbit
- Clonality Monoclonal
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from U2OS cells using db11193 at 1:1000.
订购信息
- Package Price (RMB)
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
