Cyclin D2 Rabbit pAb - diagbio | 戴格生物

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Cyclin D2 Rabbit pAb

db1117

Datasheet

Product Name : Cyclin D2 Rabbit pAb

Cat.No.: db1117

Synonyms : MPPH3; KIAK0002

Application : WB, ICC/IF, IP

Reactivity : Human

Host species : Rabbit

Background The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK4 or CDK6 and functions as a regulatory subunit of the complex, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors. Mutations in this gene are associated with megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 3 (MPPH3). [provided by RefSeq, Sep 2014]
Immunogen Recombinant protein of human Cyclin D2
Gene ID 894
Swiss Prot P30279
Synonyms MPPH3; KIAK0002
Reactivity Human
Application WB, ICC/IF, IP
Recommended dilution WB: 1:1000
ICC/IF: 1:20
IP: 1:20
Calculated MW 33 kDa
Observed MW 33 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

订购信息

Package Price (RMB)
20μL 598
50μL 998
100μL 1798
货期：现货