Vinculin Recombinant Rabbit mAb - diagbio | 戴格生物

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Vinculin Recombinant Rabbit mAb

db11158

Product Name : Vinculin Recombinant Rabbit mAb

Cat.No.: db11158

Synonyms : MV; MVCL; CMD1W; CMH15; HEL114

Application : WB, IHC

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
Immunogen Recombinant protein of human Vinculin
Gene ID 7414
Swiss Prot P18206
Synonyms MV; MVCL; CMD1W; CMH15; HEL114
Reactivity Human, Mouse, Rat
Application WB, IHC
Recommended dilution WB: 1:1000
IHC: 1:200
Calculated MW 124 kDa
Observed MW 124 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of Vinculin in K562,C6,3T3,Hela cell lysates using Vinculin antibody(1:1000 diluted).

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