Cyclin E2 Recombinant Rabbit mAb - diagbio | 戴格生物

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Cyclin E2 Recombinant Rabbit mAb

db11105

Product Name : Cyclin E2 Recombinant Rabbit mAb

Cat.No.: db11105

Synonyms : CYCE2

Application : WB, IHC, ICC/IF, FC, IP

Reactivity : Human

Host species : Rabbit

Background The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human Cyclin E2
Gene ID 9134
Swiss Prot O96020
Synonyms CYCE2
Reactivity Human
Application WB, IHC, ICC/IF, FC, IP
Recommended dilution WB: 1:1000-1:5000
IHC: 1:200-1:500
ICC/IF: 1:100-1:200
FC: 1:50
IP: 1:20
Calculated MW 47 kDa
Observed MW 47 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of Cyclin E2 in K562,Hela cell lysates using Cyclin E2 antibody(1:1000 diluted).
Western blot analysis of extracts from HCT116，A431 cells using db11105 at 1:3000.

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