GAD67 Recombinant Rabbit mAb - diagbio | 戴格生物

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GAD67 Recombinant Rabbit mAb

db11089

Product Name : GAD67 Recombinant Rabbit mAb

Cat.No.: db11089

Synonyms : GAD; SCP; CPSQ1

Application : WB, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human GAD67
Gene ID 2571
Swiss Prot Q99259
Synonyms GAD; SCP; CPSQ1
Reactivity Human, Mouse, Rat
Application WB, IP
Recommended dilution WB: 1:2000
IP: 1:20
Calculated MW 67 kDa
Observed MW 67 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of GAD67 in Hela cell lysates using GAD67 antibody(1:1000 diluted).

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