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Bak (DGR12353) Rabbit mAb
db11087
Datasheet
- Background The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008]
- Immunogen A synthetic peptide of human Bak
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Gene ID
578
-
Swiss Prot
Q16611
- Synonyms BAK; CDN1; BCL2L7; BAK-LIKE
- Reactivity Human
- Application WB, IHC-P, FC, IP
-
Recommended dilution
WB: 1:1000-1:5000
IHC-P: 1:100-1:200
FC: 1:20
IP: 1:20 - Calculated MW 23 kDa
- Observed MW 23 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR12353
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of Bak in K562,Hela cell lysates using Bak antibody(1:1000 diluted). -
Immunohistochemical analysis of paraffin-embedded human colon cancer using db11087 antibody.
订购信息
- Package Price (RMB)
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
