Bak Recombinant Rabbit mAb - diagbio | 戴格生物

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Bak Recombinant Rabbit mAb

db11087

Datasheet

Product Name : Bak Recombinant Rabbit mAb

Cat.No.: db11087

Synonyms : BAK; CDN1; BCL2L7; BAK-LIKE

Application : WB, IHC-P, FC, IP

Reactivity : Human

Host species : Rabbit

Background The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human Bak
Gene ID 578
Swiss Prot Q16611
Synonyms BAK; CDN1; BCL2L7; BAK-LIKE
Reactivity Human
Application WB, IHC-P, FC, IP
Recommended dilution WB: 1:1000-1:5000
IHC-P: 1:100-1:200
FC: 1:20
IP: 1:20
Calculated MW 23 kDa
Observed MW 23 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of Bak in K562,Hela cell lysates using Bak antibody(1:1000 diluted).
Immunohistochemical analysis of paraffin-embedded human colon cancer using db11087 antibody.

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