BackgroundThis gene encodes a member of the heat shock protein 90 family; these proteins are involved in signal transduction, protein folding and degradation and morphological evolution. This gene encodes the constitutive form of the cytosolic 90 kDa heat-shock protein and is thought to play a role in gastric apoptosis and inflammation. Alternative splicing results in multiple transcript variants. Pseudogenes have been identified on multiple chromosomes. [provided by RefSeq, Dec 2012]
Storage/StabilityStore at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Western blot detection of Hsp90 alpha/beta in Rat Brain,C6,3T3,Hela cell lysates using Hsp90 alpha/beta antibody(1:1000 diluted).
Western blot analysis of extracts from U2OS cells using db11017 at 1:6000.
Immunohistochemical analysis of paraffin-embedded human tonsil using db11017 antibody.
Immunofluorescent analysis of HeLa cells using db11017 antibody (green), and DAPI (blue).