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Bad (DGR12026) Rabbit mAb
db11004
Datasheet
- Background The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Jul 2008]
- Immunogen A synthetic peptide of human Bad
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Gene ID
572
-
Swiss Prot
Q92934
- Synonyms BBC2; BCL2L8
- Reactivity Human,Mouse,Rat
- Application WB, IHC-P, ICC/IF, FC
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Recommended dilution
WB: 1:1000
IHC-P: 1:200-1:1000
ICC/IF: 1:50
FC: 1:20-1:50 - Calculated MW 18 kDa
- Observed MW 23 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR12026
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of Bad in HeLa cell lysates using Bad antibody(1:1000 diluted). -
Western blot detection of Bad in Rat Brain,C6,3T3,Hela cell lysates using Bad antibody(1:1000 diluted). -
Immunohistochemical analysis of paraffin-embedded human breast cancer using db11004 antibody. -
Immunofluorescent analysis of HeLa cells using db11004 antibody (green), and DAPI (blue).
订购信息
- Package Price (RMB)
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
