Fibronectin (1E2) Mouse mAb - diagbio | 戴格生物

产品中心 Products Center

您当前的位置：

Fibronectin (1E2) Mouse mAb

db6465

Product Name : Fibronectin (1E2) Mouse mAb

Cat.No.: db6465

Synonyms : FN1; FN; Fibronectin; FN; Cold-insoluble globulin; CIG

Application : WB, IHC-F, IHC-P, ICC/IF

Reactivity : Human, Mouse, Rat

Host species : Mouse

Background Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts.Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling.SitesFeature keyPosition(s)Description
Immunogen Synthetic Peptide of Fibronectin
Gene ID 2335
Swiss Prot P02751
Synonyms FN1; FN; Fibronectin; FN; Cold-insoluble globulin; CIG
Reactivity Human, Mouse, Rat
Application WB, IHC-F, IHC-P, ICC/IF
Recommended dilution WB: 1:500-1:1000
IHC: 1:50-1:100
ICC/IF: 1:50-1:200
Calculated MW 272 kDa
Observed MW 285 kDa
Host species Mouse
Clonality Monoclonal
Clonality No. 1E2-6G1-3E10
Isotype IgG1
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in PBS, 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Stable for 12 months from date of receipt.

Western blot analysis of Fibronectin (1E2) in MCF-7 and Hela lysates using Fibronectin antibody.
Immunohistochemistry analysis of paraffin-embedded Human kidney using Fibronectin antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

订购信息